What if the world were coming to an end, and it was your fault?

Dr. Ben Appelstein and his archaeological team unwittingly unleash an ancient plague on the modern world, derailing their promising lives and threatening to destroy life as we know it.

Against a backdrop of war and disease, four friends fight through transformative journies both personal and monumental: Rich, a brilliant gay athlete struggling for esteem; Wendy, a querulous coed caught between two men and an uncertain future; Halfus, a quiet hero with a tragic past; and Ernie, a fun-loving charmer with aspirations of grandeur. Bound together and pulled apart, they struggle to save all they hold dear from impending doom.